A Case of Solitary Neurofibroma in Outer Surface of Nose

Abdollahi-Fakhim, Shahin and Rezaeian, Saman and Hosseinpour-Feizi, Hojjat and Naghavi-Behzad, Mohammad and Piri, Reza (2016) A Case of Solitary Neurofibroma in Outer Surface of Nose. Journal of Analytical Research in Clinical Medicine, 4 (4). pp. 233-237. ISSN 2345-4970

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Solitary neurofibroma is a benign tumor originating from Schwann cells in peripheral nerves. In an investigation of 430000 pathologic samples, only 6 cases of neurofibroma had been reported in nose and paranasal sinuses. Present patient was a 15-year-old girl with left-sided nasal and malar mass, whose CT scan and MRI showed a non-circumscribed solid mass with total thickness affecting outer part of nose in left side as well as surface and deep soft tissue. The mentioned mass underwent excision by sub-labial incision and open rhinoplasty keeping infra-orbit nerve intact. Pathologic investigation of samples showed adipose fibroblast and skeletal muscle fibers with proliferation of spindle-shaped cells and staining was negative for GFAP and positive for S-100 which represents diagnosis of neurofibroma. Main differential diagnoses of benign tumors of paranasal sinuses and nasal cavity include neurofibroma, fibroma, leiomyomas, papilloma, and schwannoma. After resection tumor should be precisely monitored, since there is malignant transformation possibility in solitary neurofibromas.

Item Type: Article
Subjects: Euro Archives > Medical Science
Depositing User: Managing Editor
Date Deposited: 04 Feb 2023 04:18
Last Modified: 04 Feb 2023 04:18
URI: http://euroarchives.uk/id/eprint/1881

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